SP11.9 Balancing Risk of Haematoma and Venous Thrombosis in VTE Prophylaxis for Breast Cancer Surgery: A Systematic Review and Meta-Analysis

Abstract Introduction Venous thromboembolism (VTE) is a largely preventable cause of morbidity and mortality in post-operative patients, however Guidelines for VTE prophylaxis breast cancer surgery are not well-established. Methods A comprehensive search was undertaken all studies that described the role surgery. Comparative reported on postoperative outcomes between patients who received (prophylaxis) those did (no prophylaxis) were included analysis. meta-analysis using random-effects model used to analyze key outcomes, with data presented as odds ratio (OR). Results total 2470 from 6 this study. Of these patient, 60.9% (n: 1504) prophylaxis. The haematoma rate study 0.05% 133). incidence significantly associated use (6.85% versus 3.11%, p: 0.001). Surgical intervention haematomas also group (3.15% 0.83%, 0.004). However there no difference events both groups (0.26% 0.36%, 0.88). Conclusion increased without any benefit preventing venous thromboembolic events. Further examine risk assessment tools high may be beneficial.